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Active Ingredients

Acetyl Hexapeptide-8

乙酰基六肽-8

Also known as: Argireline

What it does

  • Reduces expression line appearance
  • Relaxes facial muscles topically

Effective concentration

Minimum 5% Optimal 10%

Percentage refers to the solution (typically 0.005% active peptide).

Evidence

Limited evidence

Some studies show modest wrinkle reduction. Often called 'topical Botox' but effect is much milder.

Skin types

Well suited for: All

Very gentle.

Helps with

Expression Lines Fine Lines Wrinkles
Irritation potential
Very Low
Comedogenic rating
0 / 5
Pregnancy
Generally considered safe during pregnancy

Considered safe.

Good to know

Marketed as 'Botox in a bottle' but evidence is modest. Gentle, no downside to trying.

Related ingredients

Palmitoyl Pentapeptide-4 Retinol Bakuchiol Palmitoyl Tripeptide-1 Copper Tripeptide-1 Tretinoin

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Educational information only — not medical advice. Always patch test and consult a dermatologist for skin concerns.