Tretinoin
维A酸
Also known as: Retinoic Acid, Retin-A
What it does
- Most potent topical retinoid
- Anti-aging
- Acne treatment
- Cell turnover
Effective concentration
Prescription only. Start low, increase gradually.
Evidence
Strong evidenceMost studied retinoid with decades of research. FDA approved for acne and photoaging.
Skin types
Significant adjustment period. Peeling, redness, dryness common initially.
Helps with
Interactions
Increased irritation risk. Introduce slowly.
Can degrade tretinoin. Use at different times.
STRICTLY AVOID during pregnancy. Known teratogen.
Good to know
Prescription-strength retinoid. The gold standard for anti-aging. Requires sunscreen.
References
Compound data from PubChem (U.S. National Library of Medicine).
Further reading
- An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer — J Clin Med (2025)
- Optimizing Rhinoplasty Outcomes: The Role of Isotretinoin and Patient Management Strategies: Systematic Review — J Cosmet Dermatol (2025)
Selected peer-reviewed reviews on this ingredient, indexed by Europe PMC. Provided as background, not proof of any specific claim.
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Analyze a productEducational information only — not medical advice. Always patch test and consult a dermatologist for skin concerns.