Niacinamide
烟酰胺
Also known as: Vitamin B3, Nicotinamide
What it does
- Brightening and evening skin tone
- Reducing sebum production and pore appearance
- Strengthening skin barrier function
- Anti-inflammatory effects
- Improving skin texture
Effective concentration
Higher concentrations (>10%) may cause flushing without additional benefit. 5% is optimal for most people.
Evidence
Strong evidenceExtensively studied with multiple RCTs supporting efficacy for hyperpigmentation, oil control, and barrier repair.
Skin types
Well-tolerated by most skin types including sensitive skin.
Helps with
Interactions
Old myth they cancel out. Modern research shows they can be used together safely.
Considered safe during pregnancy.
Good to know
One of the most versatile and well-researched skincare actives. Great for beginners.
References
Compound data from PubChem (U.S. National Library of Medicine).
Further reading
- Nicotinamide for Skin Cancer Chemoprevention: The Jury Was Out and Still is — Am J Clin Dermatol (2026)
- Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics — Asia Pac J Clin Oncol (2026)
Selected peer-reviewed reviews on this ingredient, indexed by Europe PMC. Provided as background, not proof of any specific claim.
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Analyze a productEducational information only — not medical advice. Always patch test and consult a dermatologist for skin concerns.