COSMETIC LENS
All ingredients
Active Ingredients

Adapalene

阿达帕林

Also known as: Differin

What it does

  • Treats acne
  • Normalizes cell turnover
  • Anti-inflammatory
  • Prevents clogged pores

Effective concentration

Minimum 0.1% Optimal 0.1-0.3%

0.1% is OTC in many countries. 0.3% requires prescription.

Evidence

Strong evidence

FDA-approved for acne. More stable and less irritating than tretinoin.

Skin types

Well suited for: Oily Acne Prone
Use with caution: Sensitive Dry Eczema

Less irritating than tretinoin but still requires gradual introduction.

Helps with

Acne & Breakouts Clogged Pores Uneven Texture

Interactions

Works well with Benzoyl Peroxide

Effective combination for acne (Epiduo). Can be used together.

Irritation potential
Medium
Comedogenic rating
0 / 5
Pregnancy
Avoid during pregnancy

Retinoid—avoid during pregnancy.

Good to know

Most well-tolerated retinoid for acne. Available OTC as Differin in US/Canada/AU.

References

Compound data from PubChem (U.S. National Library of Medicine).

Further reading

Selected peer-reviewed reviews on this ingredient, indexed by Europe PMC. Provided as background, not proof of any specific claim.

Related ingredients

Tretinoin Retinol Salicylic Acid Retinal Niacinamide Retinyl Palmitate

Have a product with this ingredient?

Paste the full ingredient list to get a personalized analysis.

Analyze a product

Educational information only — not medical advice. Always patch test and consult a dermatologist for skin concerns.