Adapalene
阿达帕林
Also known as: Differin
What it does
- Treats acne
- Normalizes cell turnover
- Anti-inflammatory
- Prevents clogged pores
Effective concentration
Minimum 0.1% Optimal 0.1-0.3%
0.1% is OTC in many countries. 0.3% requires prescription.
Evidence
Strong evidenceFDA-approved for acne. More stable and less irritating than tretinoin.
Skin types
Well suited for: Oily Acne Prone
Use with caution: Sensitive Dry Eczema
Less irritating than tretinoin but still requires gradual introduction.
Helps with
Acne & Breakouts Clogged Pores Uneven Texture
Interactions
Works well with Benzoyl Peroxide
Effective combination for acne (Epiduo). Can be used together.
Irritation potential
Medium
Comedogenic rating
0 / 5
Pregnancy
Avoid during pregnancy
Retinoid—avoid during pregnancy.
Good to know
Most well-tolerated retinoid for acne. Available OTC as Differin in US/Canada/AU.
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Analyze a productEducational information only — not medical advice. Always patch test and consult a dermatologist for skin concerns.